Molecular Tests

The Joint Infection (JI) Panel provides a comprehensive approach to addressing the challenges of diagnosing septic arthritis and prosthetic joint infections. The panel delivers comprehensive results across 31 causative pathogens and eight antimicrobial resistance markers, supporting a clearer and more informed approach to the diagnosis of joint infections.

The Lactose Intolerance test identifies the C/T-13910 polymorphism (rs4988235), a specific genetic variation in the MCM6 gene that regulates the LCT (lactase) gene. This variation determines whether the ability to digest milk sugars is maintained into adulthood (lactase persistence) or naturally declines, resulting in lactase non-persistence and primary lactose intolerance.

The Meningitis/Encephalitis Panel provides a comprehensive approach to identifying the pathogens associated with meningitis and encephalitis. Distinguishing bacterial from viral meningitis based on clinical presentation alone can be challenging and, particularly in younger patients, can be a matter of life and death. The panel tests for a broad range of targets, delivering fast, pathogen-specific answers that can help save lives and guide appropriate therapy.

The Monkeypox Virus (MPXV) test detects the double-stranded DNA virus that causes mpox disease in humans and other mammals. Mpox can cause a painful rash, fever, and swollen lymph nodes, making molecular detection valuable in supporting clinical assessment.

The MTHFR A1298C variant is a highly common genetic change in the methylenetetrahydrofolate reductase gene, affecting how your body processes folate (Vitamin B9) and manages cellular methylation. In this specific variant, the expected DNA base "A" (adenine) is replaced by "C" (cytosine) at position 1298.

The MTHFR C677T is a common genetic variation (polymorphism) that changes a single building block in the MTHFR gene, reducing the efficiency of an enzyme needed to process folate (vitamin B9)

The Mycoplasma genitalium test detects Mycoplasma genitalium (Mgen), a tiny bacterium that infects the urinary and genital tracts and causes a common sexually transmitted infection (STI).

Mycoplasma hominis is a small bacterium without a cell wall that commonly inhabits the lower urogenital tract as part of normal flora, but can cause opportunistic infections when the microbiome is disrupted.

The Neisseria gonorrhoeae test detects Neisseria gonorrhoeae, a species of Gram-negative bacteria responsible for gonorrhoea, a sexually transmitted infection.

The PAI-1 4G/5G polymorphism is a common genetic variation in the promoter region of the SERPINE1 gene, which controls the production of Plasminogen Activator Inhibitor-1 (PAI-1). PAI-1 is the primary inhibitor of tissue plasminogen activator (tPA), meaning it blocks the body's ability to dissolve blood clots (fibrinolysis). The single nucleotide deletion/insertion variant creates either a sequence of four guanine bases (4G) or five guanine bases (5G), directly dictating baseline blood clotting tendencies.

Pneumonia patients are frequently over-treated with antibiotics because quickly identifying the pathogen responsible for their symptoms can be challenging. The Pneumonia Panel addresses this challenge with a comprehensive molecular test that identifies 33 potential pathogen targets from sputum-like and bronchoalveolar lavage (BAL)-like samples. For 15 bacterial targets, the panel also provides semi-quantitative results, helping to distinguish between colonizing organisms and potential pathogens and supporting more informed treatment decisions.

The Respiratory Panel is a frontline test designed to help clinicians quickly diagnose upper respiratory tract infections (URTIs), including COVID-19, influenza, RSV, and many others. Using multiplex PCR technology, it identifies 22 pathogen targets, providing rapid, accurate, and comprehensive results to support timely diagnosis and treatment decisions.

The Respiratory Syncytial Virus (RSV) test detects RSV, a common and contagious virus that infects the nose, throat, airways, and lungs.

The SARS-CoV-2 test detects the virus responsible for COVID-19, a respiratory infection with a wide clinical spectrum ranging from asymptomatic cases to severe illness. Due to its high transmissibility and continued public health significance, reliable molecular diagnostics play an important role in timely detection and containment.

The Treponema pallidum test detects Treponema pallidum, a corkscrew-shaped spirochete bacterium responsible for the sexually transmitted infection syphilis, as well as nonvenereal diseases such as yaws and bejel.

The Trichomonas vaginalis test detects Trichomonas vaginalis, a single-celled protozoan parasite responsible for trichomoniasis, the most common non-viral sexually transmitted infection (STI) worldwide.

The Ureaplasma parvum test detects Ureaplasma parvum, a tiny bacterium belonging to the Mycoplasmataceae family that commonly lives as a harmless organism in the human urogenital tract. It is found in the normal vaginal flora of approximately 40–80% of healthy, asymptomatic individuals. As part of the body's normal microbiome, it is not classified as a sexually transmitted infection (STI), although it can be passed through sexual contact.

The Ureaplasma urealyticum test detects Ureaplasma urealyticum, a small bacterium without a cell wall that commonly lives in the human urinary and genital tracts.

The West Nile Virus (WNV) test detects West Nile virus, a mosquito-borne, single-stranded RNA virus belonging to the Orthoflavivirus genus. The virus can cause West Nile fever and neuroinvasive diseases, making accurate molecular detection valuable in supporting clinical assessment.

The Zika Virus test detects Zika virus, a mosquito-borne virus that often causes no symptoms or only mild fever and rash. However, infection during pregnancy can lead to severe birth defects, making molecular detection valuable in supporting clinical assessment.